What are Biologically-Active Serums?
“Biologically active” does not mean "alive." It means the ingredients interact with living skin cells, receptors, or pathways to produce measurable physiological effects—such as repair, hydration, or regeneration—beyond simple passive moisturizing. Biologically-active serums do not require refrigeration or special handling, however, once opened, the ingredients become unstable and will degrade in 24-48 hours.
Key Characteristics of Biologically Active Ingredients
- Targeted Interaction: Binds to skin cell receptors or modulates pathways (e.g., collagen synthesis, inflammation control).
- Evidence-Supported: Backed by in vitro, ex vivo, or clinical studies (varies by ingredient).
- Concentration & Delivery: Efficacy depends on dose, pH, penetration depth, and molecular stability.
- Bioavailability: Must reach the viable epidermis or dermis in its active form.
How This Applies to StériDERM Serums
- Pharma-Grade Hyaluronic Acid: Dual-action—binds water and CD44 receptors to signal hydration, repair and promote the growth of collagen.
- PDRN (Polydeoxyribonucleotide): Derived from salmon DNA fragments, activates A2A/VEGF receptors to boost collagen production and fibroblast proliferation while reducing inflammation.
- Peptides: Mimic natural signals (matrikines) to activate fibroblasts and boost collagen/elastin.
- Purified Growth Factors (e.g., EGF, bFGF): Bind cell receptors to promote proliferation, migration, and tissue regeneration.
- DNA Repair Enzymes (NAD + FAD + Coenzyme A + Cocarboxylase): Support NAD/FAD pathways to correct UV-induced DNA damage, such as thymine dimers, and protect against photodamage.
- Amino Acids: Support protein synthesis and select antioxidant functions for barrier health.
In short: StériDERM delivers dynamic, cell-communicating skincare—not passive moisture. Our sterile, EU GMP-compliant serums are optimized for microneedling and professional use, ensuring purity, safety, and transformative anti-aging results.
