Product Overview

PHARMA-GRADE StériDERM HyalPure™ Pro starts with pharma-grade ≥99% pure (typically 99.2%–99.7%), non-cross-linked hyaluronic acid (HA) gel derived from bacterial fermentation, and enriched with PDRN (Polydeoxyribonucleotide). This biologically-active HA + PDRN combination activates A2A receptors and binds CD44 receptors on fibroblasts, triggering 300% natural collagen production while delivering intense hydration. Designed for aesthetic medical professionals, it restores skin youthfulness via microneedling, nourishes the intercellular matrix, improves elasticity and tone, and rebuilds lost structure for firm, radiant skin.

• Biologically-Active HA + PDRN: 15 mg/ml pharma-grade, non-cross-linked HA + PDRN for rapid absorption, A2A and CD44 receptor activation
• Deep Hydration: Binds up to 1,000x its weight in water (pharma-grade HA binding capacity)
• Collagen Stimulation: 300% increase via CD44 receptor binding (JID 2024) and A2A receptor activation (Clinical studies 2024-2025)
• Non-Invasive Delivery: Precision applicator syringe (used without needles) optimized for topical gel application before microneedling with StériDERM Pro Pen™
• Versatile Applications: Face, neck, décolletage, and backs of hands

COMPLETE BIOLOGICAL ACTIVITY ANALYSIS: StériDERM HyalPure™ Pro

100% BIOLOGICALLY ACTIVE (2/2 categories bioactive)

Technical Specifications

Recommended Method of Use

StériDERM HyalPure™ Pro is designed for microneedling by licensed aesthetic medical professionals using the StériDERM Pro Pen™ at a 1.0–1.5mm depth to reach the dermis and maximize A2A and CD44 receptor activation. Divide the treatment area into sections (e.g., left forehead, right forehead, left cheek, right cheek). Apply a small portion of gel evenly to one section at a time to prevent drying, and treat using a cross-hatch pattern (horizontal then vertical passes). Gently massage the area post-treatment to ensure even distribution and enhanced biological activity.

• Microneedling: Use with 12-Needle or 36-Needle Cartridge Tips at 1.0–1.5mm depth
• Treatment Protocol: 4 sessions every 3 weeks, followed by maintenance every 2 months
• Application: 2.0 ml sufficient for face, neck, backs of hands, and décolletage
• Treatment Time: 15–30 minutes per session

Pro Tip: Use with StériDERM Pro Pen™ for precise delivery and optimal A2A/CD44-driven collagen synthesis.

Clinical Benefits

Contraindications

• Not suitable for active skin infections, eczema, rosacea, psoriasis, or hypersensitivity to hyaluronic acid or PDRN
• For professional use by licensed aestheticians or medical professionals only
• Use only with sterile, single-use microneedling cartridges
• Use entire applicator syringe after opening (no preservatives)

Production & Quality

• Manufacturing: EU GMP-compliant manufacturing
• Sterility: Gamma-sterilized, single-use applicator syringe
• Material Quality: Non-animal, pharma-grade hyaluronic acid (≥99% pure) + PDRN
• Certifications: CE-marked, ISO 13485 compliant
• Shelf Life: 2 years, stored at room temperature

Packaging

• Applicator Syringe: 1 x 2.0 ml with 15 mg/ml biologically-active HA + PDRN
• Needles: None. Applicator syringe without needle is optimum for topical application before microneedling
• Preservatives: None. Use entire applicator syringe after opening